As a non-aromatizing androgen, dihydrotestosterone is extremely potent. Aromatization refers to the conversion of testosterone or anabolic steroids into estrogen. High estrogenic activity causes bloating, acne, water retention and oily skin. As dihydrotestosterone does not aromatize even at high dosages, users do not face the aforementioned side-effects. Lack of water retention also has a hardening effect on muscle tissue, in bodybuilders. Being a powerful androgen, dihydrotestosterone is also responsible for a shift in the estrogen-testosterone ratio in the body. Due to its predominant androgenic component, the steroid has a stimulating effect on the adreno-pituitary functions, and causes neurological excitation in the ‘sexual orientation areas of the brain’. This in turn, spikes sex drive in males.
Estrogenic side effects with this type of AAS are not necessary to mention, since it does not convert to estrogen. Therefore, the formation of gynecomastia, water retention and fat wrapping are not occurrence flaws. Androgenic side effects occur but to a much greater extent. It has profound effects on the scalp, which often causes hair loss, but not least relatively strong and extensive acne on the scalp, which often tends to grow to painful and scar-leaving ulcers. Also often mentioned is prostate enlargement. Noted is also slightly elevated blood pressure. It reduces the production of testosterone, like all anabolic androgenic steroids, it belongs among those with only a mild effect in this regard. Theoretically, it has a very strong potential to stimulate aggression, because it somehow negatively affects the central nervous system, but this is rather showing in women, in men it remains questionable. In long-term use, often observed are sleep disorders. Although it was used as a support drug for the treatment of cholesterol levels, in the long-term abuse decrease in HDL (good) and increase in LDL (bad) cholesterol.